10 Best Calming Products For Cats 2025 in the United States

The TherapetMD Cat Calming Diffuser is a plug-in pheromone diffuser designed to reduce anxiety and stress in cats, especially in multi-cat households. It uses a natural, vet-recommended dual-pheromone formula that mimics facial and maternal cat pheromones, helping to significantly cut down behaviors like urine spraying and scratching. One of its strengths is the 700 sq ft coverage area, making it suitable for larger rooms or shared spaces.

The diffuser works continuously once plugged in, with each refill lasting about 30 days, so it’s convenient and requires minimal effort from owners. It’s fragrance-free and safe for cats, humans, and other pets, which is important for households with multiple animals or sensitive individuals. Many users report noticeable improvements in reducing hiding, fear, and tension between cats, making it helpful during stressful events like vet visits or introducing new pets. It may take a few days to see the calming effects, and the low-glow indicator light might be hard to notice in bright settings, though this doesn’t affect the diffuser’s function.

Some cats may respond differently depending on their individual preferences, so results can vary. This diffuser provides a gentle, chemical-free way to create a calmer environment for anxious or stressed cats without hassle, although patience is needed to observe the full benefits.

The Vetoquinol Zylkene Calming Supplement is designed to help small dogs and cats manage stress from situations like travel, vet visits, or loud noises. Its main calming ingredient, alpha-casozepine, comes from a milk protein, making it a natural option that avoids drowsiness or harsh side effects commonly seen in other calming products.

This supplement is lactose-free and gentle on sensitive stomachs, which is beneficial for cats with digestive sensitivities. The package contains capsules that you open and sprinkle over your pet’s food, making it straightforward to use daily. This daily routine can support behavioral issues and help your cat stay calm during stressful events.

With a solid positive rating from many users, Zylkene offers a safe, gentle, and easy-to-administer way to support your cat’s relaxation. Pet owners should monitor their cat’s response and ensure proper dosing.

The TopSum Cat Pheromones Calming Diffuser is a plug-in device that releases synthetic cat pheromones to help reduce stress and unwanted behaviors like excessive meowing or restlessness. It comes as a 3-pack with refills, making it convenient for use in multiple rooms or for homes with several cats. Each refill lasts about 30 days, and the diffuser heads should be replaced every six months. The product is odorless, which is great if you or your cat are sensitive to smells. It’s easy to use—just plug it in and it works quietly in the background.

This diffuser suits cats of all ages, from kittens to seniors, and many owners report seeing calming effects within two weeks, though results can vary by cat. On the downside, because it relies on pheromones, it may not work for every cat or in every situation, especially if stress causes are complex. Also, since it needs to be plugged into an outlet, placement options might be limited.

As a low-effort, scent-free calming aid that covers several areas in your home and is safe for regular use, it presents a reliable choice for cat owners looking to ease their pets' anxiety.